nanosuspension相关论文
Poly(N-isopropylacrylamide)/alginate Copolymer Hydrogel Grafted Fabrics Embedding of Berberine Nanos
In the present studies,a novel hydrogel-grafted fabrics embedding of berberine nanosuspension was developed for the trea......
The purpose of this paper was to study the influence of drug physicochemical characteristics on in vitro transdermal abs......
The purpose of this paper was to study the influence of drug physicochemical characteristics on in vitro transdermal abs......
Objective: To investigate the influence of different stabilizers on the particle size of glycyrrhetinic acid (GA) nanosu......
A toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension b
Clinically, paclitaxel (PTX) is one of most commonly prescribed therapies against a wide range of solid neoplasms.Despit......
Lymphatic transport of Puerarin occurs after oral administration of different lipid-based formulatio
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Evaluation of pluronic nanosuspensions loading a novel insoluble anticancer drug both in vitro and i
Aim: The aim of this study was to prepare a nanosuspension loading a novel insoluble anticancer drug (Q39) by precipitat......
从Smoluchowski方程和Nernst-Planck方程出发, 推导出负极化纳米悬浊液中有效折射率与光强呈e指数关系, 提出了利用Airy光束在负极......
Improving The Antitumor Effect and Bioavailability of Camptothecin Loading Nanosuspension via Increa
Camptothecin(CPT) nanosuspension is prepared by anti-solvent precipitation combined with sonication with TPGS as sta......
Objective: To enhance the dissolution rate and oral bioavailability of Terminalia arjuna bark extract by formulating its......
目的:制备灯盏乙素纳米混悬液(SCU-NS),并考察制备过程中的主要影响因素。方法:通过试验确定制备工艺参数,采用单因素试验初选SCU-......
10-羟基喜树碱(HCPT)是一种广谱抗癌药,然而由于其溶解性差、不稳定,限制了它的应用.本研究采用微沉淀法联合高压均质法制备羟基喜......
本研究建立了一种快速、灵敏的定量方法,检测beagle犬口服达比加群酯纳米混悬剂后血浆中达比加群的浓度.采用液-质谱/质谱方法,使......
,Parenteral nanosuspensions: a brief review from solubility enhancement to more novel and specific a
Advancements in in silico techniques of lead molecule selection have resulted in the failure of around 70％ of new chemica......
波棱酮(herpetone,HPT)是从波棱瓜子总木脂素中分离得到的单体化合物,具有保肝降酶及抗乙肝病毒活性.然而,波棱酮存在水溶性差、生......
采用高压均质法制备阿瑞吡坦纳米混悬剂,以制备温度、均质压力和均质次数为考察对象,以粒径分布、多分散系数和?电位为评价指标,利......
采用介质研磨法制备尼莫地平纳米混悬剂以提高药物溶解度。以粒径、多分散系数(PDI)、ζ电位为指标,采用单因素法优化其处方和工艺......
对纳米混悬剂的研究进展，包括其制备方法、表征和应用进行了综述，并且介绍了纳米混悬剂技术在植物保护化学品上的应用。作为一种新的......
目的观察抗癌新药2-甲氧基雌二醇(2-ME)纳米混悬剂的安全性,为其临床试验提供依据。方法分别进行兔耳缘静脉刺激性实验和溶血性实......
目的：考察2-甲氧基雌二醇（2-ME）纳米混悬剂在肺癌荷瘤小鼠体内组织的分布特征。方法：70只昆明小鼠制作Lewis肺癌荷瘤鼠模型后随机分为2......
目的 探讨运用高压匀质技术制备齐墩果酸纳米悬浮液的可行性.方法 以纳米粒粒径及多分散指数为指标，研究各影响因素如压力、循环次......
〔目的〕通过单因素考察法筛选最适处方并制备伊曲康唑纳米混悬膜剂。〔方法〕以空白膜剂的外观和手感为指标,考察空白膜剂处方中......
目的 制备泊那替尼纳米混悬剂,并对其理化性质及体外溶出行为进行表征.方法 采用溶剂蒸发技术制备泊那替尼纳米混悬剂,利用激光纳......
目的筛选3,4,3″-三羟基对三联苯纳米混悬液的制备工艺。方法采用纳米沉淀-微射流结合法制备纳米混悬液，以粒径为考察指标，通过单因......
目的：制备非洛贝特纳米混悬剂，以促进药物溶出。方法：以非洛贝特为主药，采用熔融乳化法联合高压均质法制备纳米混悬剂；选取处方中表面活......
目的：优化阿苯达唑纳米混悬液的冻干工艺,制备阿苯达唑纳米微粉。方法：采用冷冻干燥法,以粒径、Zeta电位为指标,对预冻温度和冻干保......
制备纳米二氧化钛（TiO2）分别和729.6,1 004.5,1 168.5nm 3种粒径的磷酸锆碟片（ZrP）混合纳米悬浮液,研究了混合悬浮液的分散稳定性。运......
目的 制备冬凌草甲素粉雾剂并考察其治疗大鼠急性肺损伤的疗效.方法 沉淀法制备冬凌草甲素纳米混悬剂.筛选葡萄糖、蔗糖、乳糖和甘......
目的探讨维甲酸纳米粒混悬剂对兔眼实验性增生性玻璃体视网膜病变(PVR)的预防作用.方法新西兰白兔20只(40眼),随机分为2组:对照组......
Background and objective Previous studies have demonstrated the anti-cancer effects of propolis. However, its use is lim......
Currently, drug discovery technology is heavily dependent oncombinatorial chemistry and high throughput screening, resul......
Improved dissolution and oral absorption by co-grinding active drug probucol and ternary stabilizers
The objective of this work is to construct a nanosuspension drug delivery system of probucol,a BCS II drug,in order to i......
Objective:To enhance the dissolution rate and oral bioavailability of Terminalia arjuna bark extract by formulating its ......
